西北国防医学杂志审稿
西北国防医学杂志审稿
1,ND:YAG激光心肌再血管化远期效果实验研究,中华胸心外科杂志1996年10月第12卷第5期270。2,室间隔膜部瘤的外科治疗,西北国防医学杂志,1998年,7,19(2)126。3,常温心脏间隔缺损直视手术6例报告,西北国防医学杂志,1999,3,20(1)53。4,主动脉窦瘤破裂的外科治疗,西北国防医学杂志,2001,3,22(1)835,腋下小切口行动脉导管未闭结扎术体会,西北国防医学杂志,2001,9,22(3)227。6,二尖瓣替换术连续46例无死亡体会,西北国防医学杂志,2002,4,23(2)138。7,60例非体外循环冠状动脉旁路移植术临床总结, 西北国防医学杂志,2004,2,25(1)65。8,Cantrell综合征1例,西北国防医学杂志,2004,4,25(2)160。
西北国防医学杂志属于核心期刊吗
《西北国防医学杂志》 是 中国科技核心期刊,但不是中文核心期刊。
算是 普通国家级期刊了。
如何建立大鼠甲状腺癌模型
用左旋T_4建立大鼠甲状腺功能亢进模型的实验研究--《西北国防医学杂志》2006年01期
本文献来源中国知网
目的:用含左旋T4的药物(优甲乐)灌胃建立大鼠甲状腺功能亢进(甲亢)模型。方法:每天以两种不同剂量(60μg/100g体重,30μg/100 g体重)的优甲乐灌胃,定期记录大鼠的心率(尾动脉脉搏)、收缩压、体重,放免法测定大鼠血清T3、T4。取大鼠心脏称重及HE染色做组织病理检查。结果:甲状腺功能亢进大鼠的血清T3、T4水平较对照组明显升高(P<0.01),该组动物的心率、心脏重量,心肌细胞大小也显著高于对照组(P<0.05)。结论:优甲乐是一种有效建立大鼠甲亢模型的药物。
【作者单位】:第四军医大学西京医院核医学科 陕西西安710032
【关键词】:甲状腺功能亢进;优甲乐;T3;T4
【分类号】:R-332
【DOI】:cnki:ISSN:1007-8622.0.2006-01-015
【正文快照】:
甲状腺功能亢进症(简称甲亢,HT,Hyperthy-roid ism)是一类由于血液中甲状腺激素(T3、T4)异常增高所导致的多系统高代谢症候群以及高兴奋症状。建立大鼠甲亢模型对基础研究意义重大,以往文献报道[1~3]用干甲状腺片建立甲亢大鼠模型所需时间普遍偏长(50 d左右),本文介绍一种相对
Objective: To establish the rat's hyperthyroidism model with Euthyrox containing s: Two different doses of Euthyrox were administered to rats by intragastric tube every day,rat's heart rate(caudal(artery) pulse),systolic pressure,and body weight were detected regularly and serum T_3、T_4 concentration were(determined) by 's heart samples were removed,weighted and stained with HE to obtain the pathologic result of cardiac s: The concentrations of serum total T_3 and T_4 were increased(remarkably) in those rats with hyperthyroidism(P<0.01).Compared to control group,the rat's heart rate,weight of heart and cardiac muscle cell's transverse diameter of the experimental group increased significantly(P <(0.05)).Conclusion: Euthyrox is an effective drug to establish rat's hyperthyroidism model.
张迎梅的发表论文及专著
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Toxic effects of fluoride on reproductive ability in male rats: sperm motility, oxidative stress, cell cycle, and testicular apoptosis. Fluoride. 42(3): 174-178. (SCI)Ming Jun Yang, Jing Wu, Zhong Duo Yang*, Ying Mei Zhang*. 2009. First total synthesis of paecilodepsipeptide A. Chinese Chemical Letters. 20: 527–530. (SCI)Gen Chen, Jie Qin, Dazhong Shi, Yingmei Zhang*, Weihong Ji. 2009. Diversity of soil nematodes in areas polluted with heavy metals and polycyclicaromatic hydrocarbons (PAHs) in Lanzhou, China. Environmental Management. 44: 163-172. (SCI)Wang YJ, Meng FG, Zhang YM*. 2009. Expression, purification and characterization of recombinant protein tyrosine phosphatase from Thermus thermophilus HB27. Acta Biochimica et Biophysica Sinica. 41: 689-698. (SCI)Huang DJ, Zhang YM*, Qi YM, Chen C, Ji WH. 2008. Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of Cadmium-stimulated K562 cell proliferation. Toxicology Letters.179: 43-47. 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(SCI)Yang Liu, Yingmei Zhang*, Jianghai Liu, Dejun Huang 2006 The role of reactive oxygen species in the herbicide acetochlor-induced DNA damage on Bufo raddei tadpole liver, Aquatic Toxicology , 78:21-26.(SCI)Y. Zhang*, L. Ruan, M. Fasola, E. Boncompagni, Y. Dong, N. Dai, C. Gandini, E. Orvini and X. Ruiz 2006 Little Egrets (Egretta Garzetta) and Trace-metal Contamination in Wetlands of China, Environmental Monitoring and Assessment,118:355-368. (SCI)Jianghai Liu, Yingmei Zhang*, Dejun Huang, Gang Song. 2005. Cadmium induced MTs synthesis via oxidative stress in yeast Saccharomyces cerevisiae, Mollecular and Cellular Biochemistry, 280:139-145.(SCI)Y. M. Zhang*, D. J. Huang, Y. Q. Wang, J. H. Liu, R. L. Yu, J. Long. 2005. Heavy Metal Accumulation and Tissue Damage in Goldfish Carassius auratus. Bulletin of Environmental Contamination and Toxicology, 75: 1191-1199.(SCI)S. Lambiase, Y. Zhang, P. Morbini, M. Fasola, G. Bernocchi, E. Roda,1 A. Grigolo. 2005. Tissue damage after acute intoxication by polychlorinated biphenyls (PCBs) in cockroaches Blattella germanica, European Journal of Histochemistry, 49:83-92.(SCI)Mauro Fasola, Paolo Galeotti, Nianhua Dai, Yuanhua Dong and Yingmei Zhang. 2004. Large Numbers of Breeding Egrets and Herons in China. Waterbirds. 27(1): 126-128. (SCI), , , , & . 2004. Residues of organochlorinated pesticides in eggs of water birds from Tai Lake in China. Environmental Geochemistry and Health, 26: 259-268.(SCI)Yingmei Zhang*, Luzhang Ruan, Dongqin Zhao, Yanhua Dong. 2002. The ecology of the Little Egret as a bioindicator for Tai Lake, China. 23rd International Ornithological Congress. Abstract Volume. 129, YM, Lambiase S, Fasola M, Gandini C, Laudani U & Grigolo A. 2001. Mortality and Tissue Damage by Heavy Metal Contamination in the German Cockroach, Blattella germanica (Blattaria, Blattellidae). Ital. . 68: 137-145.(SCI)Fasola M, Zhang Y, Zhao D, Dong Y, Wang H. 2001. 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