药理学英文文献

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在药学上 PO为Per Oral的简写，意为口服。还有一些常用给药方法：im(intramscular injection)=肌肉注射；iv(intravenous injection)＝静脉注射；ivgtt或者iv by drip＝静脉滴注；ih(hypodermic injection)＝皮下注射此外，还有一些常用服药方法：qd＝每日1次；bid＝每日2次；tid＝每日3次；qid＝每日4次qw＝每周1次；qod＝隔日1次以后大家有类似问题可以直接登录鑫达医学翻译网站QQ在线咨询【专业】、【快捷】、【免费】！鑫达医学翻译 转做生物医药学翻译【百度或Google搜索 鑫达医学翻译 首条记录即是】

目的 :探讨竹叶的水溶性提取液对小鼠的抗氧化及体外清除羟自由基 (·OH-)的作用。方法 :7月龄小鼠给予竹叶提取液 (8,12g·kg-1,ig) ,连续30d后 ,采用生化方法测定小鼠全血的超氧化歧化酶 (SOD)和谷胱甘肽过氧物酶 (GSH Px)活性 ,并检测小鼠心、肝、脑组织中脂褐质 (LF)、丙二醛 (MDA)和SOD含量。采用体外抗坏血酸体系产生·OH-的原理 ,观察竹叶提取液清除·OH-的作用。结果 :给予竹叶提取液的小鼠心、肝、脑组织和全血中SOD及GSH Px活力显著提高 ,而MDA和LF含量则明显下降。竹叶提取液亦能清除抗坏血酸体系产生的·OH-,且·OH-的清除率呈明显的量效相关性 (r =0 976 )。结论 :竹叶提取液具有直接清除机体·OH-,且能提高组织中抗氧化酶的活性 ,抑制自由基损伤 ,防止脂质过氧化的作用。【作者单位】：咸宁学院药学院药理教研室;咸宁学院药学院护理系;咸宁学院药学院药理教研室;咸宁学院药学院免疫教研室;咸宁学院药学院生化教研室 咸宁437100;湖北;咸宁437100;湖北;咸宁437100;湖北;咸宁437100;湖北;咸宁437100;湖北【关键词】：竹叶;抗氧化;超氧化物歧化酶;氧自由基;羟自由基【基金】：湖北省教育厅科研基金资助项目 (№ 2 0 0 3A0 0 8)【分类号】：R5【DOI】：cnki:ISSN:1009-2004-05-025【正文快照】： 竹叶是禾木科多年生常绿乔木或灌木植物淡竹的叶片,在我国具有悠久的食用和药用历史。竹叶性淡、微涩、寒,味甘、苦。近年来对竹叶提取物药用价值和保健功能的研究才刚起步,研究表明,竹叶中的总黄酮含量与银杏叶具有可比性,竹叶还含有大量的活性多糖成分和丰富的微量元素,具有 AIM: To study the antioxidant effects of extract solution of bamboo leaves in mice and the effects of scavenging hydroxyl free radical ( ·OH- ) in METHODS: The mice were treated with extract solution of bamboo leaves (8,12 g·kg -1 ,ig) daily for 30 The activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in blood and the contents of lipofuscin (LF),malondialdehyde (MDA) and SOD in liver,and brain and heart by biochemical methods were ·OH- was induced by ascorbate-Cu 2+ reaction system,and the effect of extract solution of bamboo leaves on scavenging ·OH- was estimated by RESULTS: The extract solution of bamboo leaves could significantly increase the activities of SOD and GSH-Px in blood and the activities of SOD in liver,brain and heart in mice,and obviously reduce the contents of LF and MDA in mice The extract solution of bamboo leaves of 05 - 0 g·L -1 had markedly effects on scavenging ·OH- from 8 % to 7 % in dose-effect relationship (r= 976 ) CONCULSION: The extract solution of bamboo leaves can obviously inhibit damage of free radical and prevent lipid The mechanisms may associate with directly scavenging ·OH- ,and with increasing the activities of antioxidation enzymes in mice