bmc医学杂志

这个属于还是上层级别的呀，毕竟BMC杂志还是非常可以的呢，还是非常不错呀。所以还是属于上层级别的led。

BMC杂志在世界上属什么级别？P53, Somatostatin receptor 2a and Chromogranin A immunostaining as prognostic markers in high grade gastroenteropancreatic neuroendocrine neoplasms.Abstract:BACKGROUND:High grade gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) with a Ki67 proliferation index > 20%, include well-differentiated tumours grade 3 (NET G3) and poorly differentiated (PD) neuroendocrine carcinomas (NEC). Abnormal p53-expression is a feature of PD tumours, while expression of chromogranin A (CgA) and somatostatin-receptor 2a (SSTR-2a) may be a feature of well-differentiated tumours. The aim of this study was to elucidate the expression and prognostic value of these three markers in 163 GEP-NEN patients with a Ki67-index > 20%. METHOD:Clinical data, histopathology and overall survival were analysed according to Kaplan-Meier's method and Cox regression. The expression of SSTR-2a, CgA and synaptophysin was analysed in tumour specimens by immunohistochemistry, and semi-quantitatively scored as negative ( 30%). P53 was defined as normal when scored as heterogeneously positive (1-30%), and abnormal when negative (0%) or strongly positive (> 30%). RESULTS:In multivariate analysis, better survival was observed among patients with heterogeneously positive p53 compared to strongly positive (p  20%. Patients with heterogeneously positive p53 had the best prognosis. SSTR-2a was a positive prognostic marker in pancreatic NEN. Negative CgA was associated with a significantly worse OS compared to heterogeneously positive CgA-expression in a multivariate sub-analysis. Lower Ki67 index correlated significantly with heterogeneously positive p53, positive SSTR-2a and CgA expression.展开更多BMC CANCERBMC CANCER最新影响因子：期刊ISSN：1471-2407研究方向：医学-肿瘤学CiteScore：出版年份：2001出版地区：ENGLAND出版周期：Bimonthly是否OA：YES期刊官方网址：...期刊投稿网址：期刊coverage：Science Citation Index Expanded （科学引文索引扩展）NCBI查询：PubMed Central (PMC)链接全文检索 (pubmed central)

不好投。BMCMedicine是BMC旗下医学领域的旗舰期刊。作为一本开放获取、公开同行评议的期刊，BMCMedicine旨在发表杰出且具有影响力的研究，涵盖领域包括临床实践、转化医学、医学健康进展、公共卫生、全球卫生、公共卫生政策以及其他生物医学、社会医学专业研究人员可能感兴趣的主题。同时，期刊也发表围绕争议话题的辩论和综述、见解独到的会议投稿以及简明的指南等。

不是 BMC是网络版杂志。 BioMed Central(以下简称BMC)是生物医学领域的一家独立的新型出版社,以出版网络版期刊为主,目前出版120种生物学和医学领域的期刊