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(1) Li W, Zheng J, Deng J, You Y, Wu H, Li N, Lu J,Zhou Y*. Increased Levels of the Long Noncoding RNA POU3F3 Promote DNA Methylation in Esophageal Squamous Cell Carcinoma Cells. Gastroenterology. 146(7):1714-1726;2014 .(*通讯作者,本期封面推荐文章)(2) Wu H, Zheng J, Deng J, Hu M, You Y, Li N, Li W, Lu J, Zhou Y*. A genetic polymorphism in is associated with susceptibility to esophageal squamous cell carcinoma in Chinese populations. Carcinogenesis. 34(12):2908-17; 2013.(*通讯作者)(3) Zheng J, Deng J, Xiao M, Yang L, Zhang L, You Y, Hu M, Li N, Wu H, Li W, Lu J, Zhou Y*. A sequence polymorphism in miR-608 predicts recurrence after radiotherapy for nasopharyngeal carcinoma. Cancer Res. 73(16):5151-62; 2013. (*通讯作者)(4) Wu H, Deng J, Zheng J, You Y, Li N, Li W, Wu D, Zhou Y*. Functional polymorphisms in the CD44 gene and acute myeloid leukemia cancer risk in a Chinese population. Mol Carcinog. 2013 Sep 4. [Epub ahead of print] (*通讯作者)(5) Zheng J, Deng J, Jiang L, Yang L, You Y, Hu M, Li N, Wu H, Li W, Li H, Lu J, Zhou Y*. Heterozygous genetic variations of FOXP3 in elevate breast cancer risk in Chinese population via skewed X-chromosome inactivation. Hum Mutat. 34(4):619-28; 2013.(*通讯作者)(6) You Y, Deng J, Zheng J, Hu M, Li N, Wu H, Li W, Lu J, Zhou Y*. IL-21 gene polymorphism is associated with the prognosis of breast cancer in Chinese populations. Breast Cancer Res Treat. 137(3):893-901;2013.(*通讯作者)(7) Li N, Xu Y, Zheng J, Jiang L, You Y, Wu H, Li W, Wu D, Zhou Y*. NBS1 rs1805794G>C polymorphism is associated with decreased risk of acute myeloid leukemia in a Chinese population. Mol Biol Rep. 40(5):3749-56; 2013.(*通讯作者)(8) Zheng J, Jiang L, Zhang L, Yang L, Deng J, You Y, Li N, Wu H, Li W, Lu J, Zhou Y*. Functional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populations. Carcinogenesis. 33(12):2409-16; 2012.(*通讯作者)(9) Jiang L, Deng J, Zhu X, Zheng J, You Y, Li N, Wu H, Lu J, Zhou Y*. CD44 rs13347 C>T polymorphism predicts breast cancer risk and prognosis in Chinese populations. Breast Cancer Res. 14(4):R105; 2012.(*通讯作者)(10) Hu M, Jian L, Zhang L, Zheng J, You Y, Deng J, Li H, Zhou Y*. Functional polymorphism in the EpCAM gene is associated with occurrence and advanced disease status of cervical cancer in Chinese population. Mol Biol Rep. 39(7):7303-9;2012.(*通讯作者)(11) Hu Y, Jiang L, Zheng J, You Y, Zhou Y*, Jiao S. Association between the p73 exon 2 G4C14-to-A4T14 polymorphism and cancer risk: a meta-analysis. DNA Cell Biol. 31(2):230-7; 2012.(*通讯作者)(12) Zheng J, Chen S, Jiang L, You Y, Wu D, Zhou Y*. Functional genetic variations of cyclooxygenase-2 and susceptibility to acute myeloid leukemia in a Chinese population. Eur J Haematol. 87(6):486-93; 2011.(*通讯作者)(13) Zheng J, Liu B, Zhang L, Jiang L, Huang B, You Y, Jiang Q, Zhang S, Lu J, Zhou Y*. The protective role of polymorphism MKK4-1304 T>G in nasopharyngeal carcinoma is modulated by Epstein-Barr virus' infection status. Int J Cancer. 130(9):1981-90;2012.(*通讯作者)(14) Zheng J, Zhang C, Jiang L, You Y, Liu Y, Lu J, Zhou Y*. Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma. Mol Carcinog. 50(9):689-96; 2011.(*通讯作者)(15) Jiang L, Zhou P, Sun A, Zheng J, Liu B, You Y, Zhang C, Wu D, Zhou Y*. Functional variant (-1304T>G) in the MKK4 promoter is associated with decreased risk of acute myeloid leukemia in a southern Chinese population. Cancer Sci. 102(8):1462-8; 2011.(*通讯作者)(16) Yu X, Zhang C, Sun A, Jiang L, Zheng J, You Y, Wu D, Zhou Y*. Genetic variations in CD14 promoter and acute lymphoblastic leukemia susceptibility in a Chinese population. DNA Cell Biol. 30(10):777-82;2011.(*通讯作者)(17) Jiang L, Liang J, Jiang M, Yu X, Zheng J, Liu H, Wu D, Zhou Y*. Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population. Eur J Haematol. 86(3):199-205; 2011.(*通讯作者)(18) Jiang L, Zhang C, Li Y, Yu X, Zheng J, Zou P, Li Y, Bin X, Lu J, Zhou Y*. A non-synonymous polymorphism Thr115Met in the EpCAM gene is associated with an increased risk of breast cancer in Chinese population. Breast Cancer Res Treat. 126(2):487-95;2011.(*通讯作者)(19) Zheng J, Zhang C, Jiang L, You Y, Liu Y, Lu J, Zhou Y*. Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma. Mol Carcinog. 50(9):689-96; 2011.(*通讯作者)(20) Xu J, He X, Jin L, Jiang L, Zhou Y*, Kang Z, Peng R, Lee ST. A protein-based electrochemical method for label-free characterization of sequence-specific protein-DNA interactions. Electrochim Acta. 56:5759-5765; 2011.(*通讯作者)(21) Jiang L, Zhou P, Sun A, Zheng J, Liu B, You Y, Zhang C, Wu D, Zhou Y*. Functional variant (-1304T>G) in the MKK4 promoter is associated with decreased risk of acute myeloid leukemia in a southern Chinese population. Cancer Sci. 102(8):1462-8; 2011.(*通讯作者)(22) Yu X, Zhang C, Sun A, Jiang L, Zheng J, You Y, Wu D, Zhou Y*. Genetic variations in CD14 promoter and acute lymphoblastic leukemia susceptibility in a Chinese population. DNA Cell Biol. 30(10):777-82;2011.(*通讯作者)(23) Jiang L, Liang J, Jiang M, Yu X, Zheng J, Liu H, Wu D, Zhou Y*. Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population. Eur J Haematol. 86(3):199-205; 2011.(*通讯作者)(24) Zheng J, Yu X, Jiang L, Xiao M, Bai B, Lu J, Zhou Y*. Association between the Cytotoxic T-lymphocyte antigen 4 +49G > A polymorphism and cancer risk: a meta-analysis. BMC Cancer. 10:522; 2010.(*通讯作者)(25) Gao Y, He Y, Ding J, Wu K, Hu B, Liu Y, Wu Y, Guo B, Shen Y, Landi D, Landi S, Zhou Y*, Liu H. An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma. Carcinogenesis. 30(12):2064-9;2009.(*通讯作者)(26) Sun T, Zhou Y*, Yang M, Hu Z, Tan W, Han X, Shi Y, Yao J, Guo Y, Yu D, Tian T, Zhou X, Shen H, Lin D. Functional genetic variations in CTLA-4 and susceptibility to multiple types of cancer. Cancer Res. 2008 68:7025-7034.(*共同第一作者) (27) Sun T, Zhou Y*, Li H, Han X, Shi Y, Wang L, Miao X, Tan W, Zhao D, Zhang X, Guo Y, Lin D. FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer. J Exp Med. 2005 202:967-974.(*共同第一作者)(28) Zhou Y, Yu C, Miao X, Wang Y, Tan W, Sun T, Zhang X, Xiong P, Lin D. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis. 2005 26:1117-1121.(29) Yu C, Zhou Y*, Miao X, Xiong P, Tan W, Lin D. Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer. Cancer Res. 2004 64:7622-7628.(*共同第一作者)(30) Zhou Y, Yu C, Miao X, Tan W, Liang G, Xiong P, Sun T, Lin D. Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes. Carcinogenesis. 2004 25:399-404.(31) Yang L, Yang X, Ji W, Deng J, Qiu F, Yang R, Fang W, Zhang L, Huang D, Xie C, Zhang H, Zhong N, Ran P, Zhou Y, Lu J. Effects of a Functional Variant >C in Snai1 on Risk of Two Contextual Diseases. Chronic Obstructive Pulmonary Disease and Lung Cancer. Am J Respir Crit Care Med. 189(2):139-48; 2014.(32) Yang L, Liu B, Qiu F, Huang B, Li Y, Huang D, Yang R, Yang X, Deng J, Jiang Q, Zhou Y,Lu J. The effect of functional MAPKAPK2 copy number variation CNV-30450 on elevating nasopharyngeal carcinoma risk is modulated by EBV infection. Carcinogenesis. 35(1):46-52; 2014.(33) Yang R, Yang L, Qiu F, Zhang L, Wang H, Yang X, Deng J, Fang W, Zhou Y, Lu J. Functional genetic polymorphisms in PP2A subunit genes confer increased risks of lung cancer in southern and eastern Chinese. PLoS One. 8(10):e77285; 2013.(34) Wu C, Li D, Jia W, Hu Z, Zhou Y, Yu D, Tong T, Wang M,Lin D, Qiao Y, Zhou Y, Chang J, Zhai K, Wang M, Wei L, Tan W, Shen H, Zeng Y,Lin D. Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma. Nat Genet. 45(6):632-8; 2013.(35) Qiu F, Yang L, Fang W, Li Y, Yang R, Yang X, Deng J, Huang B, Xie C, Zhou Y,Lu J. A functional polymorphism in the promoter of ERK5 gene interacts with tobacco smoking to increase the risk of lung cancer in Chinese populations. Mutagenesis. 28(5):561-7; 2013.(36) Cheng M, Yang L, Yang R, Yang X, Deng J, Yu B, Huang D, Zhang S, Wang H, Qiu F, Zhou Y,Lu J. A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. Carcinogenesis. 34(10):2292-9; 2013.(37) Wu C, Chang J, Ma B, Miao X, Zhou Y, Liu Y, Li Y, Wu T, Hu Z, Shen H, Jia W, Zeng Y,Lin D, Kraft P. The case-only test for gene-environment interaction is not uniformly powerful: an empirical Epidemiol. 37(4):402-7; 2013.(38) Xie C, Yang L, Yang X, Yang R, Li Y, Qiu F, Chen M, Fang W, Bin X, Deng J, Huang D, Liu B, Zhou Y, Lu J. Sipa1 promoter polymorphism predicts risk and metastasis of lung cancer in Chinese. Mol Nov; [Epub ahead of print](39) Yang L, Liu B, Huang B, Deng J, Li H, Yu B, Qiu F, Cheng M, Wang H, Yang R, Yang X, Zhou Y, Lu J. A functional copy number variation in WWOX gene is associated with lung cancer risk in Chinese. Hum Mol Genet. 22(9):1886-94; 2013.(40) Huang D, Yang L, Liu Y, Zhou Y, Guo Y, Pan M, Wang Y, Tan Y, Zhong H, Hu M, Lu W, Ji W, Wang J, Ran P, Zhong N, Zhou Y, Lu J. Functional polymorphisms in NFκB1/IκBα predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese. Hum Genet. 2013 Jan 16. [Epub ahead of print](41) Huang L, Wu C, Yu D, Wang C, Che X, Miao X, Zhai K, Chang J, Jiang G, Yang X, Cao G, Hu Z, Zhou Y, Zuo C, Wang C, Zhang X,Zhou Y, Yu X, Dai W, Li Z, Shen H, Liu L, Chen Y, Zhang S, Wang X, Liu Y, Sun M, Cao W, Gao J, Ma Y, Zheng X, Cheung ST, Jia Y, Tan W, Wu T, Lin D. Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer. Carcinogenesis. 34(5):1001-5; 2013.(42) Jin G, Ma H, Wu C, Dai J, Zhang R, Shi Y, Lu J, Miao X, Wang M, Zhou Y, Chen J, Li H, Pan S, Chu M, Lu F, Yu D, Jiang Y, Dong J, Hu L, Chen Y, Xu L, Shu Y, Pan S, Tan W, Zhou B, Lu D, Wu T, Zhang Z, Chen F, Wang X, Hu Z, Lin D, Shen H. Genetic variants at and are associated with risk of multiple cancers in Han Chinese. Am J Hum Genet. 91(5):928-34; 2012.(43) Yang L, Qiu F, Lu X, Huang D, Ma G, Guo Y, Hu M, Zhou Y, Pan M, Tan Y, Zhong H, Ji W, Wei Q, Ran P, Zhong N, Zhou Y, Lu J. Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese. PLoS One. 7(10):e46071;2012.(44) You Y, Deng J, Zheng J, Jiang L, Li N, Wu H, Li W, Lu J, Zhou Y, Ni B. Functional polymorphisms in PIN1 promoter and esophageal carcinoma susceptibility in Chinese population. Mol Biol Rep. 40(2):829-38;2013.(45) Wu C, Kraft P, Zhai K, Chang J, Wang Z, Li Y, Hu Z, He Z, Jia W, Abnet CC, Liang L, Hu N, Miao X, Zhou Y, Liu Z, Zhan Q, Liu Y, Qiao Y, Zhou Y, Jin G, Guo C, Lu C, Yang H, Fu J, Yu D, Freedman ND, Ding T, Tan W, Goldstein AM, Wu T, Shen H, Ke Y, Zeng Y, Chanock SJ, Taylor PR, Lin D. Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nat Genet. 44(10):1090-7;2012.(46) Liu B, Yang L, Huang B, Cheng M, Wang H, Li Y, Huang D, Zheng J, Li Q, Zhang X, Ji W, Zhou Y, Lu J. A functional copy-number variation in MAPKAPK2 predicts risk and prognosis of lung cancer. Am J Hum Genet. 91(2):384-90; 2012.(47) Huang D, Qiu F, Yang L, Li Y, Cheng M, Wang H, Ma G, Wang Y, Hu M, Ji W, Zhou Y, Lu J. The polymorphisms and haplotypes of WWOX gene are associated with the risk of lung cancer in southern and eastern Chinese populations. Mol Carcinog. 2012 Jun 12. [Epub ahead of print](48) Yang M, Sun T, Zhou Y, Wang L, Liu L, Zhang X, Tang X, Zhou M, Kuang P, Tan W, Li H, Yuan Q, Yu D. The functional cytotoxic T lymphocyte-associated Protein 4 49G-to-A genetic variant and risk of pancreatic cancer. Cancer. 118(19):4681-6; 2012.(49) Huang B, Liu B, Yang L, Li Y, Cheng M, Huang D, Wang H, Zhang X, Zheng J, Li Q, Ji W, Zhou Y, Lu J. Functional genetic variants of c-Jun and their interaction with smoking and drinking increase the susceptibility to lung cancer in southern and eastern Chinese. Int J Cancer. 131(5):E744-58; 2012.(50) Yang L, Li Y, Cheng M, Huang D, Zheng J, Liu B, Ling X, Li Q, Zhang X, Ji W, Zhou Y, Lu J. A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population. Carcinogenesis. 33(2):338-47;2012.(51) Wu C, Miao X, Huang L, Che X, Jiang G, Yu D, Yang X, Cao G, Hu Z, Zhou Y, Zuo C, Wang C, Zhang X, Zhou Y, Yu X, Dai W, Li Z, Shen H, Liu L, Chen Y, Zhang S, Wang X, Zhai K, Chang J, Liu Y, Sun M, Cao W, Gao J, Ma Y, Zheng X, Cheung ST, Jia Y, Xu J, Tan W, Zhao P, Wu T, Wang C, Lin D. Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations. Nat Genet. 44(1):62-6; 2011.(52) Shi Y, Hu Z, Wu C, Dai J, Li H, Dong J, Wang M, Miao X, Zhou Y, Lu F, Zhang H, Hu L, Jiang Y, Li Z, Chu M, Ma H, Chen J, Jin G, Tan W, Wu T, Zhang Z, Lin D, Shen H. A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at and . Nat Genet. 43(12):1215-8;2011.(53) Lu J, Yang L, Zhao H, Liu B, Li Y, Wu H, Li Q, Zeng B, Wang Y, Ji W, Zhou Y. The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations. Hum Mutat. 32(11):1299-308; 2011.(54) Wu C, Hu Z, He Z, Jia W, Wang F, Zhou Y, Liu Z, Zhan Q, Liu Y, Yu D, Zhai K, Chang J, Qiao Y, Jin G, Liu Z, Shen Y, Guo C, Fu J, Miao X, Tan W, Shen H, Ke Y, Zeng Y, Wu T, Lin D. Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. Nat Genet. 43(7):679-84; 2011.(55) Ding J, Gao Y, He Y, Zhou Y, Huang M, Liu H. Screening SNPs residing in the microRNA-binding sites of hepatocellular carcinoma related J Data Min Bioinform. 5(1):1-21; 2011.(56) Lin D, Liu C, Xue M, Liu R, Jiang L, Yu X, Bao G, Deng F, Yu M, Ao J, Zhou Y, Wu D, Liu H. The role of interleukin-15 polymorphisms in adult acute lymphoblastic leukemia. PLoS One. 5(10):e13626; 2010.(57) Liu P, Jaffar J, Zhou Y, Yang Y, Hellström I, Hellström KE. Inhibition of TGFbeta1 makes nonimmunogenic tumor cells effective for therapeutic vaccination. J Immunother. 32(3):232-9; 2009.(58) Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, Shi Y, Tan W, Zhou Y, Zhao D, Zhang X, Guo Y, Lin D. Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer. Carcinogenesis. 2007 28:1067-1073. (59) Yang Y, Yang S, Ye Z, Jaffar J, Zhou Y, Cutter E, Lieber A, Hellström I, Hellström KE. Tumor cells expressing anti-CD137 scFv induce a tumor-destructive environment. Cancer Res. 2007 67:2339-2344.(60) Hao B, Miao X, Li Y, Zhang X, Sun T, Liang G, Zhao Y, Zhou Y, Wang H, Chen X, Zhang L, Tan W, Wei Q, Lin D, He F. A novel T-77C polymorphism in DNA repair gene XRCC1 contributes to diminished promoter activity and increased risk of non-small cell lung cancer. Oncogene. 2006 25:3613-3620.(61) Zhang X, Miao X, Guo Y, Tan W, Zhou Y, Sun T, Wang Y, Lin D. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat. 2006 27:110-117.(62) Zhang X, Miao X, Sun T, Tan W, Qu S, Xiong P, Zhou Y, Lin D. Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer. J Med Genet. 2005 42:479-484.(63) Tan W, Miao X, Wang L, Yu C, Xiong P, Liang G, Sun T, Zhou Y, Zhang X, Li H, Lin D. Significant increase in risk of gastroesophageal cancer is associated with interaction between promoter polymorphisms in thymidylate synthase and serum folate . 2005 26:1430-1435.(64) Sun T, Miao X, Wang J, Tan W, Zhou Y, Yu C, Lin D. Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma. Carcinogenesis. 2004 25:2225-2230.(65) Liang G, Miao X, Zhou Y, Tan W, Lin D. A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking. Carcinogenesis. 2004 25:773-778.(66) 李华,郭红燕,孙瞳,周翊峰,林东昕,章文华,乔杰。Fas和Fas配体基因启动子单核苷酸多态性与子宫颈癌的发病风险。《中华肿瘤杂志》2009 31: 38-41.(67) 张雪梅,缪小平,谭文,曲世宁,孙瞳,周翊峰,林东昕。亚甲基四氢叶酸还原酶基因遗传变异与肺癌。《中国医学科学院学报》2005 27:700-703.(68) 冯飞跃,梁刚,吕文富,缪小平,于春媛,谭文,周翊峰,孙瞳,康滨,周彤,潘凯枫,张联,林东昕。尿苷二磷酸葡糖醛酸转移酶1A7基因多态基础研究。《癌症》2005 24:1085-1090.(69) 张雪梅,缪小平,熊萍,于春媛,谭文,曲世宁,孙瞳,周翊峰,林东昕。基质金属蛋白酶2和9功能性单核苷酸多态与胃癌。《癌症》2004 23:1233-1237

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