xian蝦米
Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a set of symptoms and infections resulting from the damage to the human immune system caused by the human immunodeficiency virus (HIV).[1] This condition progressively reduces the effectiveness of the immune system and leaves individuals susceptible to opportunistic infections and tumors. HIV is transmitted through direct contact of a mucous membrane or the bloodstream with a bodily fluid containing HIV, such as blood, semen, vaginal fluid, preseminal fluid, and breast milk.[2][3] This transmission can involve anal, vaginal or oral sex, blood transfusion, contaminated hypodermic needles, exchange between mother and baby during pregnancy, childbirth, or breastfeeding, or other exposure to one of the above bodily is now a pandemic.[4] In 2007, an estimated million people lived with the disease worldwide, and it killed an estimated million people, including 330,000 children.[5] Over three-quarters of these deaths occurred in sub-Saharan Africa,[5] retarding economic growth and destroying human capital.[6] Most researchers believe that HIV originated in sub-Saharan Africa during the twentieth century.[7] AIDS was first recognized by the . Centers for Disease Control and Prevention in 1981 and its cause, HIV, identified by American and French scientists in the early 1980s.[8]Although treatments for AIDS and HIV can slow the course of the disease, there is currently no vaccine or cure. Antiretroviral treatment reduces both the mortality and the morbidity of HIV infection, but these drugs are expensive and routine access to antiretroviral medication is not available in all countries.[9] Due to the difficulty in treating HIV infection, preventing infection is a key aim in controlling the AIDS epidemic, with health organizations promoting safe sex and needle-exchange programmes in attempts to slow the spread of the symptoms of AIDS are primarily the result of conditions that do not normally develop in individuals with healthy immune systems. Most of these conditions are infections caused by bacteria, viruses, fungi and parasites that are normally controlled by the elements of the immune system that HIV damages. Opportunistic infections are common in people with AIDS.[10] HIV affects nearly every organ system. People with AIDS also have an increased risk of developing various cancers such as Kaposi's sarcoma, cervical cancer and cancers of the immune system known as lymphomas. Additionally, people with AIDS often have systemic symptoms of infection like fevers, sweats (particularly at night), swollen glands, chills, weakness, and weight loss.[11][12] The specific opportunistic infections that AIDS patients develop depend in part on the prevalence of these infections in the geographic area in which the patient infections X-ray of Pneumocystis jirovecii caused pneumonia. There is increased white (opacity) in the lower lungs on both sides, characteristic of Pneumocystis pneumoniaPneumocystis pneumonia (originally known as Pneumocystis carinii pneumonia, and still abbreviated as PCP, which now stands for Pneumocystis pneumonia) is relatively rare in healthy, immunocompetent people, but common among HIV-infected individuals. It is caused by Pneumocystis jirovecii. Before the advent of effective diagnosis, treatment and routine prophylaxis in Western countries, it was a common immediate cause of death. In developing countries, it is still one of the first indications of AIDS in untested individuals, although it does not generally occur unless the CD4 count is less than 200 cells per µL of blood.[13]Tuberculosis (TB) is unique among infections associated with HIV because it is transmissible to immunocompetent people via the respiratory route, is easily treatable once identified, may occur in early-stage HIV disease, and is preventable with drug therapy. However, multidrug resistance is a potentially serious problem. Even though its incidence has declined because of the use of directly observed therapy and other improved practices in Western countries, this is not the case in developing countries where HIV is most prevalent. In early-stage HIV infection (CD4 count >300 cells per µL), TB typically presents as a pulmonary disease. In advanced HIV infection, TB often presents atypically with extrapulmonary (systemic) disease a common feature. Symptoms are usually constitutional and are not localized to one particular site, often affecting bone marrow, bone, urinary and gastrointestinal tracts, liver, regional lymph nodes, and the central nervous system.[14]Gastrointestinal infectionsEsophagitis is an inflammation of the lining of the lower end of the esophagus (gullet or swallowing tube leading to the stomach). In HIV infected individuals, this is normally due to fungal (candidiasis) or viral (herpes simplex-1 or cytomegalovirus) infections. In rare cases, it could be due to mycobacteria.[15]Unexplained chronic diarrhea in HIV infection is due to many possible causes, including common bacterial (Salmonella, Shigella, Listeria or Campylobacter) and parasitic infections; and uncommon opportunistic infections such as cryptosporidiosis, microsporidiosis, Mycobacterium avium complex (MAC) and viruses,[16] astrovirus, adenovirus, rotavirus and cytomegalovirus, (the latter as a course of colitis). In some cases, diarrhea may be a side effect of several drugs used to treat HIV, or it may simply accompany HIV infection, particularly during primary HIV infection. It may also be a side effect of antibiotics used to treat bacterial causes of diarrhea (common for Clostridium difficile). In the later stages of HIV infection, diarrhea is thought to be a reflection of changes in the way the intestinal tract absorbs nutrients, and may be an important component of HIV-related wasting.[17]Neurological and psychiatric involvementHIV infection may lead to a variety of neuropsychiatric sequelae, either by infection of the now susceptible nervous system by organisms, or as a direct consequence of the illness is a disease caused by the single-celled parasite called Toxoplasma gondii; it usually infects the brain, causing toxoplasma encephalitis, but it can also infect and cause disease in the eyes and lungs.[18] Cryptococcal meningitis is an infection of the meninx (the membrane covering the brain and spinal cord) by the fungus Cryptococcus neoformans. It can cause fevers, headache, fatigue, nausea, and vomiting. Patients may also develop seizures and confusion; left untreated, it can be multifocal leukoencephalopathy (PML) is a demyelinating disease, in which the gradual destruction of the myelin sheath covering the axons of nerve cells impairs the transmission of nerve impulses. It is caused by a virus called JC virus which occurs in 70% of the population in latent form, causing disease only when the immune system has been severely weakened, as is the case for AIDS patients. It progresses rapidly, usually causing death within months of diagnosis.[19]AIDS dementia complex (ADC) is a metabolic encephalopathy induced by HIV infection and fueled by immune activation of HIV infected brain macrophages and microglia. These cells are productively infected by HIV and secrete neurotoxins of both host and viral origin.[20] Specific neurological impairments are manifested by cognitive, behavioral, and motor abnormalities that occur after years of HIV infection and are associated with low CD4+ T cell levels and high plasma viral loads. Prevalence is 10–20% in Western countries[21] but only 1–2% of HIV infections in India.[22][23] This difference is possibly due to the HIV subtype in India. AIDS related mania is sometimes seen in patients with advanced HIV illness; it presents with more irritability and cognitive impairment and less euphoria than a manic episode associated with true bipolar disorder. Unlike the latter condition, it may have a more chronic course. This syndrome is less often seen with the advent of multi-drug and malignancies Kaposi's sarcomaPatients with HIV infection have substantially increased incidence of several cancers. This is primarily due to co-infection with an oncogenic DNA virus, especially Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV), and human papillomavirus (HPV).[24][25]Kaposi's sarcoma (KS) is the most common tumor in HIV-infected patients. The appearance of this tumor in young homosexual men in 1981 was one of the first signals of the AIDS epidemic. Caused by a gammaherpes virus called Kaposi's sarcoma-associated herpes virus (KSHV), it often appears as purplish nodules on the skin, but can affect other organs, especially the mouth, gastrointestinal tract, and B cell lymphomas such as Burkitt's lymphoma, Burkitt's-like lymphoma, diffuse large B-cell lymphoma (DLBCL), and primary central nervous system lymphoma present more often in HIV-infected patients. These particular cancers often foreshadow a poor prognosis. In some cases these lymphomas are AIDS-defining. Epstein-Barr virus (EBV) or KSHV cause many of these cancer in HIV-infected women is considered AIDS-defining. It is caused by human papillomavirus (HPV).[26]In addition to the AIDS-defining tumors listed above, HIV-infected patients are at increased risk of certain other tumors, such as Hodgkin's disease and anal and rectal carcinomas. However, the incidence of many common tumors, such as breast cancer or colon cancer, does not increase in HIV-infected patients. In areas where HAART is extensively used to treat AIDS, the incidence of many AIDS-related malignancies has decreased, but at the same time malignant cancers overall have become the most common cause of death of HIV-infected patients.[27]Other opportunistic infectionsAIDS patients often develop opportunistic infections that present with non-specific symptoms, especially low-grade fevers and weight loss. These include infection with Mycobacterium avium-intracellulare and cytomegalovirus (CMV). CMV can cause colitis, as described above, and CMV retinitis can cause blindness. Penicilliosis due to Penicillium marneffei is now the third most common opportunistic infection (after extrapulmonary tuberculosis and cryptococcosis) in HIV-positive individuals within the endemic area of Southeast Asia.[28]
楠辉之恋
"The Black Cat" is a short story by Edgar Allan Poe. It was first published in the August 19, 1843, edition of The Saturday Evening Post. It is a study of the psychology of guilt, often paired in analysis with Poe's "The Tell-Tale Heart".[1] In both, a murderer carefully conceals his crime and believes himself unassailable, but eventually breaks down and reveals himself, impelled by a nagging reminder of his guilt. The story is presented as a first-person narrative using an unreliable narrator. The narrator tells us that from an early age he has loved animals. He and his wife have many pets, including a large black cat named Pluto. This cat is especially fond of the narrator and vice versa. Their mutual friendship lasts for several years, until the narrator becomes an alcoholic. One night, after coming home intoxicated, he believes the cat is avoiding him. When he tries to seize it, the panicked cat bites the narrator, and in a fit of rage, he seizes the animal, pulls a pen-knife from his pocket, and deliberately gouges out the cat's that moment onward, the cat flees in terror at his master's approach. At first, the narrator is remorseful and regrets his cruelty. "But this feeling soon gave place to irritation. And then came, as if to my final and irrevocable overthrow, the spirit of PERVERSENESS." He takes the cat out in the garden one morning and hangs it from a tree, where it dies. That very night, his house mysteriously catches on fire forcing the narrator, his wife and their servant to next day, the narrator returns to the ruins of his home to find, imprinted on the single wall that survived the fire, the figure of a gigantic cat, hanging by its neck from a first, this image terrifies the narrator, but gradually he determines a logical explanation for it, that someone outside had thrown the dead cat into the bedroom to wake him up during the fire, and begins to miss Pluto. Some time later, he finds a similar cat in a tavern. It is the same size and color as the original and is even missing an eye. The only difference is a large white patch on the animal's chest. The narrator takes it home, but soon begins to loathe, even fear the creature. After a time, the white patch of fur begins to take shape and, to the narrator, forms the shape of the , one day when the narrator and his wife are visiting the cellar in their new home, the cat gets under its master's feet and nearly trips him down the stairs. In a fury, the man grabs an axe and tries to kill the cat but is stopped by his wife. Enraged, he kills her with the axe instead. To conceal her body he removes bricks from a protrusion in the wall, places her body there, and repairs the hole. When the police came to investigate, they find nothing and the narrator goes free. The cat, which he intended to kill as well, has gone the last day of the investigation, the narrator accompanies the police into the cellar. There, completely confident in his own safety, the narrator comments on the sturdiness of the building and raps upon the wall he had built around his wife's body. A wailing sound fills the room. The alarmed police tear down the wall and find the wife's corpse, and on her head, to the horror of the narrator, is the screeching black cat. As he words it: "I had walled the monster up within the tomb!" Like the narrator in Poe's "The Tell-Tale Heart", the narrator of "The Black Cat" has questionable sanity. Near the beginning of the tale, the narrator says he would be "mad indeed" if he should expect a reader to believe the story, implying that he has already been accused of madness.[2]One of Poe's darkest tales, "The Black Cat" includes his strongest denouncement of alcohol. The narrator's perverse actions are brought on by his alcoholism, a "disease" and "fiend" which also destroys his personality.[3] The use of the black cat evokes various superstitions, including the idea voiced by the narrator's wife that they are all witches in disguise. The titular cat is named Pluto after the Roman god of the Underworld. Publication history"The Black Cat" was first published in the August 19, 1843 issue of The Saturday Evening Post. At the time, the publication was using the temporary title United States Saturday Post.[4] Readers immediately responded favorably to the story, spawning parodies including Thomas Dunn English's "The Ghost of the Grey Tadpole".[5][edit] Adaptations [edit] In film "The Black Cat" was adapted into a film starring Bela Lugosi and Boris Karloff in 1934 and another with Lugosi and Basil Rathbone in 1941, although neither version bears much resemblance to the original story.[5] Many other adaptations exist but the most faithful to the original is the middle segment of Roger Corman's trilogy film Tales of Terror in 1962.[5] Although the overall film was cast with Vincent Price as the lead, in this segment, he was in a supporting role with Peter Lorre as the main character. The 1934 film Maniac also loosely adapts the story. This version follows a former vaudeville actor who kills a doctor and takes the doctor's place to hide his crime. "The Black Cat" was also adapted into a film of the same name by Italian horror director Lucio Fulci in 1981. Film director Dario Argento presented his own loose adaptation of the story in the 1990 anthology film Two Evil Eyes.[edit] In television "The Black Cat" is the eleventh episode of the second season of Masters of Horror. The plot essentially retells the short story in a semi-autobiographical manner, with Poe himself undergoing a series of events involving a black cat which he used to inspire the story of the same name.[edit] Recordings In 1997, a compilation of Poe's work was released on a double CD entitled Closed on Account of Rabies, with various celebrities lending their voices to the tales. The Black Cat was read by avant-garde performer Diamanda Galás.[edit] References in literary works In 1970, Czech writer Ludvík Vaculík made many references to "A Descent into the Maelstr�0�2m" as well as "The Black Cat" in his novel The Guinea Pigs.[edit] References in art In 1910-11 Futurist artist Gino Severini painted "The Black Cat" in direct reference to Poe's short story. An illustration and description can be found at this site
CISSYZHANG74
1、猫艾滋病的定义猫艾滋病（FelineImmunodeficiencyVirus，FIV）是一种由猫免疫缺陷病毒引起的慢性传染病，可以导致猫的免疫系统受损，从而容易感染其他疾病。目前猫艾滋病还没有被完全治愈，因此预防措施十分重要。一旦猫被感染，应尽早采取措施，延缓病情的恶化。2、猫感染艾滋病的原因猫艾滋病的传播途径主要是通过感染了病毒的动物或猫的体液直接接触传播，如唾液、血液、精液、乳汁等。感染途径包括亲密接触、共用饮食用具、野生猫的接触、交配等。此外，在医疗过程中也有可能传播该病毒，如手术切口、牙齿缝隙、注射等。猫艾滋病属于病毒病，目前无特效药治疗，因此彻底清除猫艾滋病毒比较困难。3、猫感染艾滋病的症状猫感染艾滋病后，由于免疫系统受损，容易出现多种感染，如口腔炎、皮肤病、呼吸道疾病等。常见症状包括消瘦、愈合缓慢的伤口、发热、呕吐、腹泻、黄疸等。一般来说，猫艾滋病病毒进入猫体内后，需要一段时间才会出现明显的症状，这个时间长度因个体而异。在此期间，病毒随时可以通过猫的体液传播给其他猫。4、如何预防猫感染艾滋病预防猫感染艾滋病的最好方法就是防止猫暴露在感染病毒的环境中。应该避免让猫到室外游荡，不让它与未知病毒的猫接触。此外，要定期进行身体检查和血液检测，确保猫身体健康。如果家中有多只猫，应该让它们进行艾滋病疫苗的接种，这样可以有效地保护它们免受感染。可以根据宠物医院的指引，按时带猫接受疫苗注射，以保证疫苗的效果和接种的周期。
艾滋病来源于猩猩和猴子之说一时引起人们的恐慌，因为在20世纪50年代末期，美国费城的威斯塔研究所曾经使用黑猩猩的肾脏生产了几批脊髓灰质炎疫苗。这些用于生产疫苗的
招财KItty. 4人参与回答 2023-12-11 有那么一群人，走到哪里人们都畏惧，或许他们身体会被隔离，或许那颗心总很孤寂，朋友远离，亲人抛弃。他们恐惧，恐惧下一个清晨初升的太阳已不属于自己。他们成为了疾病的
fabregas89 4人参与回答 2023-12-09 忘记了是从那一天起,爱滋病这个略带西方色彩的字眼闯如了我们的生活.它惊醒了沉睡中的我们.让我们认识了爱滋,了解了爱滋,惧怕了爱滋,远离了爱滋病人. 人性就在这时
西由位门1 3人参与回答 2023-12-08 Today, I was at home with nothing to do. I didn't know what to do with my though
布丁无敌 4人参与回答 2023-12-08 爱滋病传播途径及预防方法 摘要:艾滋病的医学全称为:"获得性免疫缺陷综合症",英文缩写"AIDS",是由人体感染人类免疫缺陷病毒即艾滋病毒(HIV)引起的免疫缺
黄金哇塞赛 4人参与回答 2023-12-08 