李建勇白血病期刊论文

1988年毕业于北京医科大学（现北京大学医学部）医学系，1991年、1997年获苏州医学院（现苏州大学医学院）硕士、博士学位，师从中国工程院院士阮长耿教授长。1997年6-7月，英国皇家自由医院大规模单抗制备技术，1997年12月-1998年11月法国南特大学医院中心博士后，开展多发性骨髓瘤的荧光原位杂交研究。1991年7月-2001年3月，苏州大学附属第一医院血液科、江苏省血液研究所工作，历任医师、主治医师、副主任医师、血液科副主任、血研所副所长，2001年4月始在江苏省人民医院工作，2007年12月-2008年3月组团德国乌尔姆大学专项进修慢性淋巴细胞白血病基础与临床研究专业领域： 一直从事血液病的临床及科研工作，擅长利用多参数流式细胞术、荧光原位杂交技术及分子生物学技术对恶性血液病诊断分型、预后判断、病情监测，并根据患者的临床生物学特征采取个体化治疗策略。据国内领先水平。目前主要研究方向为淋巴增殖性疾病，主要开展慢性淋巴细胞白血病诊断、鉴别诊断、预后相关因素、发病机制及临床治疗研究。起草了《中国慢性淋巴细胞白血病诊断与治疗专家共识》（中华血液学杂志2010年第2期）。在亚洲居于领先水平。 学术团体任职情况： 中华医学会血液学分会委员、中国实验血液学会委员、中国抗癌协会血液学分会委员、江苏省血液学会副主任委员、南京市血液学会主任委员。中华血液学杂志、中国实验血液学杂志、国际输血及血液学杂志、南京医科大学学报、白血病淋巴瘤等5种杂志的编委。 近 五年在国内外核心期刊上发表学术论文情况： 论文题目刊物名称刊物国家收录情况卷期排名 The investigation of mutation and single nucleotide polymorphism of receptor tyrosine kinases and downstream scaffold molecules in acute myeloid leukemia Leuk Lymphoma 国外 SCI 2006,47⑿：2610-6 通讯 Effect of low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming (CAG regimen) on the outcome of elderly patients with acute myeloid leukemia Leuk Res 国外 SCI 2007,31⑽：1383-8 通讯 Interphase fluorescence in situ hybridization detection of cytogenetic abnormalities in B-cell chronic lymphocytic leukemia Int J Hematol 国外 SCI 2007,85⑸：430-6 通讯 MicroRNA gene expression in malignant lymphoproliferative disorders Chin Med J 国内 SCI 2007,120⑾：996-9 通讯 The prognostic evaluation of CLLU1 expression levels in 50 Chinese patients with chronic lymphocytic leukemia Leuk Lymphoma 国外 SCI 2007,48⑼：1785-92 通讯 Prognostic significance of ATM and TP53 deletions in Chinese patients with chronic lymphocytic leukemia Leuk Res 国外 SCI 2008,32⑺：1071-7 通讯 Outcome of treatment with Hyper-CVAD regimen in Chinese patients with acute lymphocytic leukemia Leuk Res 国外 SCI 2008,32⑹：930-5 通讯 Successful application of nonmyeloablative stem cell transplantation for paroxysmal nocturnal hemoglobinuria Chin Med J 国内 SCI 2007,120（22）：2056-8 通讯 JAK2 V617F patients with essential thrombocythemia present with clinical features of polycythemia vera Leuk Lymphoma 国外 SCI 2008,49⑷：696-9 通讯 MPL W515L mutation in Chinese patients with myeloproliferative diseases Leuk Lymphoma 国外 SCI 2008,49⑸：955-8 通讯 Expression level of lipoprotein lipase in Chinese patients with chronic lymphocytic leukemia and its correlation with other prognostic factors Int J Lab Hematol 国外 SCI 2009,31⑸：552-9. 通讯 Trisomy 22 as the sole abnormality is an important marker for the diagnosis of acute myeloid leukemia with inversion 16 Onkologie 国外 SCI 2008,31（8-9）：440-4 通讯 An analysis of complex chromosomal aberrations in seven cases of myelodysplastic syndromes by M-FISH and whole chromosome painting Int J Hematol 国外 SCI 2008,88⑷：369-73 通讯 An update of molecular pathogenesis and diagnosis of myeloproliferative disorders in the JAK2 era Chin Med J 国内 SCI 2008,20;121⒅：1838-42 通讯 The negative prognostic impact of derivative 9 deletions in patients who received hydroxyurea treatment for chronic myelogenous leukemia in the chronic phase Onkologie 国外 SCI 2008,31⑾：585-9 第一 CD38 as a prognostic factor in Chinese patients with chronic lymphocytic leukaemia Leuk Res 国外 SCI 2009,33⑵：237-43 通讯 Nonhematological autoimmunity (glomerulosclerosis,paraneoplastic pemphigus and paraneoplastic neurological syndrome) in a patient with chronic lymphocytic leukemia: diagnosis,prognosis and managemen Leuk Res 国外 SCI 2009,33⑶：500-5 通讯 Bortezomib in combination with dexamethasone for a young multiple myeloma with t（8;14） Leuk Res 国外 SCI 2009,33⑷：584-6 第一 Flow cytometric assay of phosphotyrosine levels in Bcr-Abl-positive chronic myelogenous leukemias: a potential prognostic marker Ann Hematol 国外 SCI 2009,88⑴：29-36 通讯 Clinical features and outcome of Chinese patients with monoclonal B-cell lymphocytosis Leuk Res 国外 SCI 2009,33⑿：1619-22. 通讯 The decrease of JAK2 V617F allele burden in leukemia transformation of an elderly patient with myelofibrosis Leuk Res 国外 SCI 2009,33⑻：e116-118 通讯 Molecular cytogenetic aberrations in 21 Chinese patients with plasma cell leukemia Int J Lab Hematol 国外 SCI 2009,31⑶：338-343 通讯 GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism Leuk Res 国外 SCI 2009,33⑻：1141-1143. 通讯 Trisomy 8 in two newly diagnosed Chinese patients with chronic lymphocytic leukemia Cancer Genet Cytogenet 国外 SCI 2009,192⑵：79-81 通讯 The negative prognostic significance of positive direct antiglobulin test in Chinese patients with chronic lymphocytic leukemia Leuk Lymphoma 国外 SCI 2009,50⑼：1482-7 通讯 Serum thymidine kinase 1 concentration in Chinese patients with chronic lymphocytic leukemia and its correlation with other prognostic factors Int J Hematol 国外 SCI 2009,90⑵：205-211 通讯 Cotransplantation of HLA-identical mesenchymal stem cells and hematopoietic stem cells in Chinese patients with hematologic diseases Int J Lab Hematol 国内 SCI 2009 Jul 28. [Epub ahead of print] 通讯 Multiplex fluorescence in situ hybridization in identifying chromosome involvement of complex karyotypes in de novo myelodysplastic syndromes and acute myeloid leukemia Int J Lab Hematol 国内 SCI 2010,32（1 Pt 1）：e86-95. 通讯 The analysis of JAK2 and MPL mutations and JAK2 single nucleotide polymorphisms in MPN patients by MassARRAY assay Int J Lab Hematol 国外 SCI 2010 Mar 23. [Epub ahead of print] 通讯