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Wang X, Wang H, Wang J,…, Yin Y…, Brassica rapa Genome Sequencing Project Consortium. (2011) The genome of the mesopolyploid crop species Brassica rapa. Nature Genetics. 2011 Aug 28;43(10):1035-9. 岳桂东,高强,罗龙海,王军一,许娇卉,尹烨 (2012) 高通量测序技术在动植物研究领域中的应用.中国科学,42(2): 107-124. Gao Q, Yue GD, Li WQ, Wang JY, Xu JH, Yin Y. (2012) Recent progress using high-throughput sequencing technologies in plant molecular breeding. Journal of Integrative Plant Biology, 54(4):215-27. Qiu Q, Zhang G, Ma T,…, Yin Y, ….(2012) The yak genome and adaptation to life at high altitude. Nature Genetics. 2012 Jul 1;44(8):946-9. Kunbo Wang, Zhiwen Wang, Fuguang Li, …, Ye Yin,…. (2012) The draft genome of a diploid cotton Gossypium raimondii. Nature Genetics. 2012 Aug 26; 44(10):1098–1103 Zhang G, Fang X, Guo X, …, Yin Y, Wang J. (2012) The oyster genome reveals stress adaptation and complexity of shell formation.Nature. 2012 Oct 4;490(7418):49-54. David M Altshuler, Richard M Durbin, Goncalo R Abecasis...Yin Y...(2012)An integrated map of genetic variation from 1,092 human genomes. Nature. 2012 November 1; 491(7422): 56–65. Shaogui Guo, Jianguo Zhang, Honghe Sun, …, Ye Yin, ….(2012) The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nature Genetics. 2012 Nov 25; 45(1):51–58 Yin Y, Yue GD, Gao Q, Wang ZY,... (2012) Genome Sequence of Pedobacter arcticus sp. nov., a Sea Ice Bacterium Isolated from Tundra Soil. Journal of Bacteriology, 2012 Dec;194 (23):6688. Qixiang Zhang, Wenbin Chen, Lidan Sun, …,Ye Yin, …(2012) The genome of Prunus mume.Nature Communications, 2012,DOI: 10.1038/ncomms2290 Xiangjiang Zhan, Shengkai Pan, Junyi Wang, …, Ye Yin, …(2013) Peregrine and saker falcon genome sequences provide insights into evolution of a predatory lifestyle.Nature Genetics. 2013 March 24;45(5): 563–566 Zhuo Wang, Juan Pascual-Anaya, Amonida Zadissa,…, Ye Yin, Bronwen Aken, Guojie Zhang& Naoki Irie.(2013) The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan. Nature Genetics. 2013 April28;10.1038/ng.2615 Jinfeng Chen, Quanfei Huang, Dongying Gao...Ye Yin...(2013)Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution. Nature Communications, 2013, DOI: 10.1038/ncomms2596 Yabin Chen, Qingyan Zhang,Tao Shen … ,Ye Yin, …. (2013)Comprehensive mutation analysis by whole-exome sequencing in 41 Chinese families with Leber congenital amaurosisInvest . Ophthalmol Vis Sci. 2013 May 9(共同作者) Huang L1, Zhang Q, Li S, Guan L, Xiao X, Zhang J, Jia X, Sun W, Zhu Z, Gao Y, Yin Y, Wang P, Guo X, Wang J, Zhang Q.(2013) Exome sequencing of 47 chinese families with cone-rod dystrophy: mutations in 25 known causative genes. PLoS One. 2013 Jun 11; 8(6):e65546. Xiaosen Guo, Max Brenner, Xuemei Zhang, ..., Ye Yin, ... (2013) Whole-Genome Sequences of DA and F344 Rats with Different Susceptibilities to Arthritis,Autoimmunity, Inflammation and Cancer. Genetics, August 2013, 194(4):1017-28 Zhang C1, Li D, Zhang J,..., Yin Y, ....(2013)Mutations in ABCB6 cause dyschromatosis universalis hereditaria. J Invest Dermatol. 2013 Sep;133(9):2221-8. Tao Ma,Junyi Wang,Gongke Zhou, … ,Ye Yin, …(2013) Genomic insights into salt adaptation in a desert poplar. Nature Communications,2013, doi:10.1038/ncomms3797. Xiao JH, Yue Z, Jia LY, ..., Yin Y...(2013)Obligate mutualism within a host drives the extreme specialization of a fig wasp genome. Genome Biology,2013,14:R141 doi:10.1186 Cheng Qin, Changshui Yu, Yaou Shen, …, Ye Yin, Jiping Yu, Kailin Hu, and Zhiming Zhang.(2014) Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. PANS, 2014,doi/10.1073/pnas.1400975111 Udpa N, Ronen R, Zhou D,..., Yin Y...(2014)Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biology. 2014 Feb 20;15(2):R36. Shiqiang Li, Liping Guan, Shaohua Fang, ..., Ye Yin, ...(2014) Exome sequencing reveals CHM mutations in six families with atypical choroideremia initially diagnosed as retinitis pigmentosa. International Journal of Molecular Medicine,2014 June 6, DOI: 10.3892 Xu Y1, Guan L, Shen T, ..., Yin Y, Guo X, Wang J, Zhang Q.(2014) Mutations of 60 known causative genes in 157 families with retinitis pigmentosa based on exome sequencing. Hum Genet. 2014 Jun 18. Su Z, Labaj PP, Li S, ..., Yin Y, ... (2014) A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. Nature Biotechnology. 2014 Sep; 32(9):903-14. Xinfen Yu, Tao Jin, Yujun Cui, ..., Ye Yin, ...(2014) Coexistence of influenza H7N9 and H9N2 in poultry linked to human H7N9 infection and their genome characteristics. journal of Virology. 2014 Mar, 88(6):3423-31. Huiguang Wu, Xuanmin Guang, Mohamed B. Al-Fageeh...Ye Yin,...(2014)Camelid genomes reveal evolution and adaptation to desert environments. Nature Communications. 21 October 2014, doi:10.1038/ncomms6188 Haihua Bai, Xiaoshen Guo, Dong Zhang, ... Ye Yin,...(2014)The genome of a mongolian individual reveals the genetic imprints of mongolians on modern human populations.Genome Biology and Evolution. 5 November 2014, 6(12):3122-3136 Xiangyu Ma, Liping Guan, Wei Wu,...Ye Yin, ...(2015) Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa. Scientific Report. 2015 Mar 18;5:9236. doi: 10.1038/srep09236. Zhang H1, Gao Y, Jiang F,...Yin Y,...(2015)Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies. Ultrasound Obstet Gynecol. 2015; 45: 530–538Published online 8 April 2015 in Wiley Online Library . DOI:10.1002/uog.14792.

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不锈冰theresa

尹烨2002年加入华大基因分支——北京华大吉比爱生物技术有限公司,先后从事体外诊断试剂研发、产品注册、生产管理、质量管理、市场营销等工作,在生物产品研发、生产、质控、申报注册及生物技术临床应用推广等方面有丰富的经验,主持申报多项专利,数十项体外诊断试剂,对于GMP/IVD/ISO系列质量管理体系有深刻理解。2003年春,尹烨作为“非典型性肺炎”早期诊断科研攻关的主要参与者之一,在华大高效完成SARS病毒测序和获得诊断蛋白之后,他率领团队在24小时内即完成了SARS诊断试剂盒全部研发及申报材料的准备并顺利获得了国药局的审批。随后,华大及时将30万人份“免疫检测试剂盒”免费送到了防治SARS的第一线。2009年,因综合表现突出,尹烨调入华大基因总部,负责基因组学及生物信息学全球范围内的产业推广,并先后出任华大基因科技合作事业部总裁、全球生产平台负责人、华大基因研究院助理院长 ,华大集团首席运营官 ,华大医学执行总裁等职 。他负责组建起华大基因全球营销团队,打造华大基因全球化科研、产业平台,完成了华大的全球化布局。期间,尹烨先后担任全球“千种动植物基因组计划”总指挥,“百万人重测序计划”第一负责人,“蒙古高原特色物种基因组计划”总负责人,“蒙古族人基因组计划”项目主持人等,主持或参与了上百个国际基因组合作项目,在Nature等国际顶级学术期刊发表多篇论文,并推进建立华大与全球生物科研机构良好合作关系,为推动基因组学研究、分子育种、医疗健康、环境能源等领域的科研发展及为广大普通民众提供前沿生物科技在医疗、农业、环境及能源等领域的应用服务做出重要贡献。在任华大医学执行总裁期间,全面贯彻个体化、预测、干预、参与“4P医学”理念,推动了基因检测的临床应用发展,以降低出生缺陷及重大疾病对人类健康的危害。华大基因在2013年成功完成对美国上市公司Complete Genomics的全资收购,尹烨 在华大此次海外收购过程中作为核心成员起到了关键作用,积累了丰富的资本运作和融投资经验。目前,尹烨任华大基因股份有限公司执行总裁 ,率领团队积极推动前沿生物技术和基因组学研究成果的产业化 应用,向全球顶尖的医疗机构、科研机构、大学、药厂、育种公司等提供完整的基因组学解决方案,为临床行为提供诊断、干预和治疗依据,为生命科学及医学创新提供技术和研究服务,致力于成为全球基因科技应用服务行业领导者。2014年获中国十大经济潮流人物奖 2015年获评大连理工大学“2014校友年度人物”青年校友成就奖

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